Faculty Profile

Lesley Arnold

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Lesley Arnold, MD, is a doctor with University of Cincinnati Physicians.

Practice Location:
UC Health Psychiatry (Stetson Building)
260 Stetson Street
Suite 3200
Cincinnati, OH 45219

Clinical Specialties:
Psychiatry/Psychology, Fibromyalgia, Chronic Fatigue Syndrome, Depression, Women's Health Research Program

To make an appointment, please call (513) 475-8000.

 



  • Lesley Arnold, MD
  • Professor of Psychiatry; Director of the Women’s Health Research Program
  • Academic Location:
    UC Department of Psychiatry and Behavioral Neuroscience
    PO Box 670559
    Cincinnati, OH 45267-0559
  • Clinical Location:
    UC Health Psychiatry (Stetson Building)
    260 Stetson Street, Suite 3200
    Cincinnati, OH 45219
  • Phone: (513) 558-7700
  • Email: lesley.arnold@uc.edu

    Research/Clinical Interests:

  • Research interests include Fibromyalgia, Chronic Pain, Women’s Health, and Mood and Anxiety Disorders.

    Education/Credentials:

  • Bachelor: Cornell University
  • Medical Degree: University of Cincinnati College of Medicine
  • Residency: University of Cincinnati College of Medicine

Peer Reviewed Publications (in chronological order):

  • Kashikar-Zuck, S., Johnston, M., Ting, T. V., Graham, B. T., Lynch-Jordan, A. M., Verkamp, E., Passo, M., Schikler, K. N., Hashkes, P. J., Spalding, S., Banez, G., Richards, M. M., Powers, S. W., Arnold, L. M., & Lovell, D. (2010). (In Press). Relationship between School Absenteeism and Depressive Symptoms among Adolescents with Juvenile Fibromyalgia. . Journal of Pediatric Psychology , 35 (9) , 996-1004.
  • Arnold, L. M., Clauw, D., Wang, F., Ahl, J., Gaynor, P. J., & Wohlreich, M. M. (2010). (In Press). Flexible Dosed Duloxetine in the Treatment of Fibromyalgia: A Randomized, Double-blind, Placebo-controlled Trial. . The Journal of Rheumatology.
  • Kashikar-Zuck, S., Flowers, S. R., Verkamp, E., Ting, T. V., Lynch-Jordan, A. M., Graham, T. B., Passo, M., Schikler, K. N., Hashkes, P. J., Spalding, S., Banez, G., Richards, M. M., Powers, S. W., Arnold, L. M., & Lovell, D. (2010). (In Press). Actigraphy-based physical activity monitoring in adolescents with juvenile primary fibromyalgia syndrome. . The Journal of Pain : Official Journal of the American Pain Society , 11 (9) , 885-93.
  • Arnold, L. M., & Clauw, D. J. (2010). (In Press). Fibromyalgia syndrome: practical strategies for improving diagnosis and patient outcomes. . The American Journal of Medicine , 123 (6) , S2.
  • Arnold, Lesley M (2010). (In Press). The pathophysiology, diagnosis and treatment of fibromyalgia. . The Psychiatric Clinics of North America , 33 (2) , 375-408.
  • Arnold, L. M., Gendreau, R. M., Palmer, R. H., Gendreau, J. F., & Wang, Y. (2010). (In Press). Efficacy and safety of milnacipran 100 mg/day in patients with fibromyalgia: Results of a randomized, double-blind, placebo-controlled trial. . Arthritis and Rheumatism.
  • Arnold, L., Mease, P., & Silverman, S. (2010). (In Press). Pregabalin: an alpha2-delta (alpha2-delta) ligand for the management of fibromyalgia. . The American Journal of Managed Care , 16 (5 Suppl) , S138-43.
  • Arnold, Lesley M (2009). (In Press). Strategies for managing fibromyalgia. . The American Journal of Medicine , 122 (12 Suppl) , S31-43.
  • Hudson, J. I., Arnold, L. M., Bradley, L. A., Choy, E. H. S., Mease, P. J., Wang, F., Ahl, J., & Wohlreich, M. M. (2009). (In Press). What makes patients with fibromyalgia feel better? Correlations between Patient Global Impression of Improvement and changes in clinical symptoms and function: a pooled analysis of 4 randomized placebo-controlled trials of duloxetine. . The Journal of Rheumatology , 36 (11) , 2517-22.
  • Arnold, Lesley M (2009). (In Press). Advances in the management of fibromyalgia. . CNS Spectrums , 14 (10 Suppl 8) , 12-6; discussion 17-.
  • Choy, E. H., Arnold, L. M., Clauw, D. J., Crofford, L. J., Glass, J. M., Simon, L. S., Martin, S. A., Strand, C. V., Williams, D. A., & Mease, P. J. (2009). (In Press). Content and criterion validity of the preliminary core dataset for clinical trials in fibromyalgia syndrome. . The Journal of Rheumatology , 36 (10) , 2330-4.
  • Mease, P., Arnold, L. M., Choy, E. H., Clauw, D. J., Crofford, L. J., Glass, J. M., Martin, S. A., Morea, J., Simon, L., Strand, C. V., & Williams, D. A. (2009). (In Press). Fibromyalgia syndrome module at OMERACT 9: domain construct. . The Journal of Rheumatology , 36 (10) , 2318-29.
  • Arnold, Lesley M (2009). (In Press). Pain and the brain: chronic widespread pain. . The Journal of Clinical Psychiatry , 70 (4) , e10.
  • Arnold, L. M., Clauw, D. J., Wohlreich, M. M., Wang, F., Ahl, J., Gaynor, P. J., & Chappell, A. S. (2009). (In Press). Efficacy of duloxetine in patients with fibromyalgia: pooled analysis of 4 placebo-controlled clinical trials. . Primary Care Companion to the Journal of Clinical Psychiatry , 11 (5) , 237-44.
  • Arnold, L. M., Bradley, L. A., Clauw, D. J., Glass, J. M., & Goldenberg, D. L. (2008). (In Press). Multidisciplinary care and stepwise treatment for fibromyalgia. . The Journal of Clinical Psychiatry , 69 (12) , e35.
  • Arnold, L. M., Bradley, L. A., Clauw, D. J., Glass, J. M., & Goldenberg, D. L. (2008). (In Press). Evaluating and diagnosing fibromyalgia and comorbid psychiatric disorders. . The Journal of Clinical Psychiatry , 69 (10) , e28.
  • Arnold, L. M., Jain, R., & Glazer, W. M. (2008). (In Press). Pain and the brain. . The Journal of Clinical Psychiatry , 69 (9) , e25.
  • Arnold, L. M., Crofford, L. J., Mease, P. J., Burgess, S. M., Palmer, S. C., Abetz, L., & Martin, S. A. (2008). (In Press). Patient perspectives on the impact of fibromyalgia. . Patient Education and Counseling , 73 (1) , 114-20.
  • Arnold, L. M., Russell, I. J., Diri, E. W., Duan, W. R., Young, J. P., Sharma, U., Martin, S. A., Barrett, J. A., & Haig, G. (2008). (In Press). A 14-week, randomized, double-blinded, placebo-controlled monotherapy trial of pregabalin in patients with fibromyalgia. . The Journal of Pain : Official Journal of the American Pain Society , 9 (9) , 792-805.
  • Mease, P. J., Arnold, L. M., Crofford, L. J., Williams, D. A., Russell, I. J., Humphrey, L., Abetz, L., & Martin, S. A. (2008). (In Press). Identifying the clinical domains of fibromyalgia: contributions from clinician and patient Delphi exercises. . Arthritis and Rheumatism , 59 (7) , 952-60.
  • Russell, I. J., Mease, P. J., Smith, T. R., Kajdasz, D. K., Wohlreich, M. M., Detke, M. J., Walker, D. J., Chappell, A. S., & Arnold, L. M. (2008). (In Press). Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. . Pain , 136 (3) , 432-44.
  • Mease, P. J., Russell, I. J., Arnold, L. M., Florian, H., Young, J. P., Martin, S. A., & Sharma, U. (2008). (In Press). A randomized, double-blind, placebo-controlled, phase III trial of pregabalin in the treatment of patients with fibromyalgia. . The Journal of Rheumatology , 35 (3) , 502-14.
  • Lawrence, R. C., Felson, D. T., Helmick, C. G., Arnold, L. M., Choi, H., Deyo, R. A., Gabriel, S., Hirsch, R., Hochberg, M. C., Hunder, G. G., Jordan, J. M., Katz, J. N., Kremers, H. M., & Wolfe, F. (2008). (In Press). Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. . Arthritis and Rheumatism , 58 (1) , 26-35.
  • Arnold, Lesley M (2008). (In Press). Management of fibromyalgia and comorbid psychiatric disorders. . The Journal of Clinical Psychiatry , 69 Suppl 2 , 14-9.
  • Arnold, L. M., Pritchett, Y. L., D'Souza, D. N., Kajdasz, D. K., Iyengar, S., & Wernicke, J. F. (2007). (In Press). Duloxetine for the treatment of fibromyalgia in women: pooled results from two randomized, placebo-controlled clinical trials. . Journal of Women's Health (2002) , 16 (8) , 1145-56.
  • Arnold, Lesley M (2007). (In Press). Duloxetine and other antidepressants in the treatment of patients with fibromyalgia. . Pain Medicine (Malden, Mass.) , 8 Suppl 2 , S63-74.
  • Pigott, T. A., Prakash, A., Arnold, L. M., Aaronson, S. T., Mallinckrodt, C. H., & Wohlreich, M. M. (2007). (In Press). Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder. . Current Medical Research and Opinion , 23 (6) , 1303-18.
  • Mease, P., Arnold, L. M., Bennett, R., Boonen, A., Buskila, D., Carville, S., Chappell, A., Choy, E., Clauw, D., Dadabhoy, D., Gendreau, M., Goldenberg, D., Littlejohn, G., Martin, S., Perera, P., Russell, I. J., Simon, L., Spaeth, M., Williams, D., & Crofford, L. (2007). (In Press). Fibromyalgia syndrome. . The Journal of Rheumatology , 34 (6) , 1415-25.
  • Arnold, L. M., Goldenberg, D. L., Stanford, S. B., Lalonde, J. K., Sandhu, H. S., Keck, P. E., Welge, J. A., Bishop, F., Stanford, K. E., Hess, E. V., & Hudson, J. I. (2007). (In Press). Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial. . Arthritis and Rheumatism , 56 (4) , 1336-44.
  • Strakowski, S. M., DelBello, M. P., Fleck, D. E., Adler, C. M., Anthenelli, R. M., Keck, P. E., Arnold, L. M., & Amicone, J. (2007). (In Press). Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania. . Archives of General Psychiatry , 64 (1) , 57-64.
  • Arnold, L. M., Hudson, J. I., Keck, P. E., Auchenbach, M. B., Javaras, K. N., & Hess, E. V. (2006). (In Press). Comorbidity of fibromyalgia and psychiatric disorders. . The Journal of Clinical Psychiatry , 67 (8) , 1219-25.
  • Arnold, Lesley M (2006). (In Press). Management of psychiatric comorbidity in fibromyalgia. . Current Psychiatry Reports , 8 (3) , 241-5.
  • Arnold, Lesley M (2006). (In Press). Biology and therapy of fibromyalgia. New therapies in fibromyalgia. . Arthritis Research & Therapy , 8 (4) , 212.
  • Arnold, L. M., Rosen, A., Pritchett, Y. L., D'Souza, D. N., Goldstein, D. J., Iyengar, S., & Wernicke, J. F. (2005). (In Press). A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder. . Pain , 119 (1-3) , 5-15.
  • Arnold, Lesley M (2005). (In Press). The nature of painful and somatic complaints in depressive disorders. . CNS Spectrums , 10 (12 Suppl 19) , 4-5.
  • Mease, P. J., Clauw, D. J., Arnold, L. M., Goldenberg, D. L., Witter, J., Williams, D. A., Simon, L. S., Strand, C. V., Bramson, C., Martin, S., Wright, T. M., Littman, B., Wernicke, J. F., Gendreau, R. M., & Crofford, L. J. (2005). (In Press). Fibromyalgia syndrome. . The Journal of Rheumatology , 32 (11) , 2270-7.
  • Strakowski, S. M., DelBello, M. P., Fleck, D. E., Adler, C. M., Anthenelli, R. M., Keck, P. E., Arnold, L. M., & Amicone, J. (2005). (In Press). Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania. . Archives of General Psychiatry , 62 (8) , 851-8.
  • Hudson, J. I., Arnold, L. M., Keck, P. E., Auchenbach, M. B., & Pope, H. G. (2004). (In Press). Family study of fibromyalgia and affective spectrum disorder. . Biological Psychiatry , 56 (11) , 884-91.
  • Arnold, L. M., & Hudson, J. I. (2004). (In Press). Comment on: Familial aggregation of depression in fibromyalgia: a community-based test of alternative hypotheses, Raphael et al., Pain 110 (2004) 449-460. . Pain , 112 (3) , 409-10; author reply.
  • McElroy, S. L., Shapira, N. A., Arnold, L. M., Keck, P. E., Rosenthal, N. R., Wu, S., Capece, J. A., Fazzio, L., & Hudson, J. I. (2004). (In Press). Topiramate in the long-term treatment of binge-eating disorder associated with obesity. . The Journal of Clinical Psychiatry , 65 (11) , 1463-9.
  • Bennett, A. J., & Arnold, L. M. (2004). (In Press). Use of a computerized evaluation system in a psychiatry clerkship. . Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association For Academic Psychiatry , 28 (3) , 197-203.
  • Arnold, L. M., Lu, Y., Crofford, L. J., Wohlreich, M., Detke, M. J., Iyengar, S., & Goldstein, D. J. (2004). (In Press). A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. . Arthritis and Rheumatism , 50 (9) , 2974-84.
  • Arnold, L. M., Keck, P. E., Collins, J., Wilson, R., Fleck, D. E., Corey, K. B., Amicone, J., Adebimpe, V. R., & Strakowski, S. M. (2004). (In Press). Ethnicity and first-rank symptoms in patients with psychosis. . Schizophrenia Research , 67 (2-3) , 207-12.
  • Arnold, L. M., Hudson, J. I., Hess, E. V., Ware, A. E., Fritz, D. A., Auchenbach, M. B., Starck, L. O., & Keck, P. E. (2004). (In Press). Family study of fibromyalgia. . Arthritis and Rheumatism , 50 (3) , 944-52.
  • Arnold, L. M., Strakowski, S. M., Schwiers, M. L., Amicone, J., Fleck, D. E., Corey, K. B., & Farrow, J. E. (2004). (In Press). Sex, ethnicity, and antipsychotic medication use in patients with psychosis. . Schizophrenia Research , 66 (2-3) , 169-75.
  • Arnold, Lesley M (2003). (In Press). Gender differences in bipolar disorder. . The Psychiatric Clinics of North America , 26 (3) , 595-620.
  • Strakowski, S. M., Keck, P. E., Arnold, L. M., Collins, J., Wilson, R. M., Fleck, D. E., Corey, K. B., Amicone, J., & Adebimpe, V. R. (2003). (In Press). Ethnicity and diagnosis in patients with affective disorders. . The Journal of Clinical Psychiatry , 64 (7) , 747-54.
  • McElroy, S. L., Arnold, L. M., Shapira, N. A., Keck, P. E., Rosenthal, N. R., Karim, M. R., Kamin, M., & Hudson, J. I. (2003). (In Press). Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trial. . The American Journal of Psychiatry , 160 (2) , 255-61.
  • Arnold, L. M., McElroy, S. L., Hudson, J. I., Welge, J. A., Bennett, A. J., & Keck, P. E. (2002). (In Press). A placebo-controlled, randomized trial of fluoxetine in the treatment of binge-eating disorder. . The Journal of Clinical Psychiatry , 63 (11) , 1028-33.
  • Arnold, Lesley M (2002). (In Press). Phenomenology and therapeutic options for dermatotillomania. . Expert Review of Neurotherapeutics , 2 (5) , 725-30.
  • Arnold, L. M., Hess, E. V., Hudson, J. I., Welge, J. A., Berno, S. E., & Keck, P. E. (2002). (In Press). A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. . The American Journal of Medicine , 112 (3) , 191-7.
  • Arnold, Lesley M. (1999). (In Press). A Case Series of Women With Postpartum-Onset Obsessive-Compulsive Disorder. . Primary Care Companion to the Journal of Clinical Psychiatry , 1 (4) , 103-108.
  • Arnold, L. M., Hudson, J. I., Wang, F., Wohlreich, M. M., Prakash, A., Kajdasz, D. K., & Chappell, A. S. (In Press). Comparisons of the efficacy and safety of duloxetine for the treatment of fibromyalgia in patients with versus without major depressive disorder. . The Clinical Journal of Pain , 25 (6) , 461-8.
  • Arnold, L. M., Meyers, A. L., Sunderajan, P., Montano, C. B., Kass, E., Trivedi, M., & Wohlreich, M. M. (In Press). The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder. . Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists , 20 (4) , 187-93.
  • Arnold, Lesley M (In Press). Understanding fatigue in major depressive disorder and other medical disorders. . Psychosomatics , 49 (3) , 185-90.
  • Arnold, L. M., Crofford, L. J., Martin, S. A., Young, J. P., & Sharma, U. (In Press). The effect of anxiety and depression on improvements in pain in a randomized, controlled trial of pregabalin for treatment of fibromyalgia. . Pain Medicine (Malden, Mass.) , 8 (8) , 633-8.
  • Bennett, A. J., Arnold, L. M., & Welge, J. A. (In Press). Use of standardized patients during a psychiatry clerkship. . Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association For Academic Psychiatry , 30 (3) , 185-90.
  • Bennett, A. J., Roman, B., Arnold, L. M., Kay, J., & Goldenhar, L. M. (In Press). Professionalism deficits among medical students: models of identification and intervention. . Academic Psychiatry : the Journal of the American Association of Directors of Psychiatric Residency Training and the Association For Academic Psychiatry , 29 (5) , 426-32.

    Research Grants:

  • CHMC 397 / AR050028 National Institute of Arthritis, Musculoskeletal and Skin Disease. Randomized Clinical Trial in Juvenile Fibromyalgia, PI, Closed.
  • 5-N01-AR-9-2235-04-A0-S0-E0 National Institute of Arthritis, Musculoskeletal and Skin Disease. Fibromyalgia Family Study, PI, Closed.
  • National Institute of Arthritis, Musculoskeletal and Skin Disease. Phase II Double-Blind Placebo-Controlled Trial of Gabapentin in the Treatment of Fibromyalgia, PI, Closed.
  • 5-R01-AR-46054-03-A0-S0-E0 National Institute of Arthritis, Musculoskeletal and Skin Disease. A Controlled Family Study in Patients with Fibromyalgia, PI, Closed.
  • R01 AR053207 National Institute of Arthritis, Musculoskeletal and Skin Disease. Development of Fibromyalgia Responder Index, PI, Closed.
  • CHMC 105591 / R01 AR054842 National Institute of Arthritis, Musculoskeletal and Skin Disease. Longitudinal Determination of Outcomes of Adolescents with Fibromyalgia, PI, Active.
  • CK 1006212888 Pfizer, Inc.. Pfizer Visiting Professorships in Neurology/Psychiatry, PI, Closed.
  • Midwestern Pain Consortium - Consortium Agreement Eli Lilly and Company. Midwestern Pain Consortium - Consortium Agreement, PI, Active.
  • Midwestern Pain Consortium - Lilly Member Organization Agmt Eli Lilly and Company. Midwestern CTSA Pain Consortium - Lilly Member Organization Agmt, PI, Active.
Faculty Member
More Information

Department of Psychiatry and Behavioral Neuroscience

Mailing Address:
PO Box 670559
Cincinnati, OH 45267-0559

Office Location:
Stetson Building
260 Stetson Street
Suite 3200
Cincinnati, OH 45219

Phone: (513) 558-7700
Email: donna.niemeier@uc.edu